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Mechanistic experiments exposed compound forty eight induced S-stage cell cycle arrest and apoptosis in CCRF-CEM cells. The composition–exercise partnership (SAR) Examination indicated that a five,6-dimethoxy moiety plus a 2-ethyl ester group within the indole scaffold were being important for

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Indazole and The straightforward alkylindazoles are white crystalline solids. The indazole ring possesses two nitrogen atoms and might be functionalized with significant selectivity at different positions. As someone proceeds to use drugs, the Mind adapts by cutting down the flexibility of cells